An Elvitegravir Nanoformulation Crosses the Blood–Brain Barrier and Suppresses HIV-1 Replication in Microglia
نویسندگان
چکیده
منابع مشابه
Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages
Purpose Monocytes serve as sanctuary sites for HIV-1 from which virus is difficult to be eliminated. Therefore, an effective viral suppression in monocytes is critical for effective antiretroviral therapy (ART). This study focuses on a new strategy using nanoformulation to optimize the efficacy of ART drugs in HIV-infected monocytes. Methods Poly(lactic-co-glycolic acid) (PLGA)-based elvitegr...
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ژورنال
عنوان ژورنال: Viruses
سال: 2020
ISSN: 1999-4915
DOI: 10.3390/v12050564